Otto fischer



UNITED STATES PATENT OFFICE.

OTTO FISCHER, on MUNIOH, B-AVARIA, GERMANY.

METHOD OF PREPARING OXYQUINOL'INE' PECIFICATION forming part of Letters Patent No. 270,045, dated'January 2,185.3;

Application filed May 27, 1882. (No specimens.)

To allwhom it'may concern:

Beitknown thutl, ULUITO FiscnER,ofMunich, Bavaria, have invented a new and useful Improvement in theMethod ofPreparing Ox quinoline, of which the following is a specification.

This invention relates to certain new and useful improvements in the manufacture of a new antiseptic, which is known as oxyquinoline, produced. from qninoline-sulphonicacid.

In 1869 the discovery was made that qnino- I line-sulphonic acid is produced when clnchonia quinoline is treated with conccn (rated sulphuric acid. Quinoline-sulphonic acid can also be produced by the action of concentrated sulphuric acid on the quinoline of coal-tar and the artificial quinoline prepared bySkraup.

My invention consists in converting the quinoline-sulphonic acid into oxyquinoline by heating thequinoline-sulphonicacid with caustic potash or soda.

In carrying out my invention one part, by weight, ofquinoline-sulphonic acid is carefully heated in an iron melting-pan on an open fire with from one to two parts, by weight, of caustic sodaor two or threevparts, by weight, of caustic potash. The heating is continued until a sample of the molten mass on being neutral- For technical purposes a solution of the above oxyqninoline in water or in diluted acids is-employed.

Having thus fully described my invention, I claim as new and desire to secure by Let ters Patent- The method of preparing oxyquinolin'e by treating quinoline-sulphonic acid with caustic soda or potash under the action of heat,,sub;

stantially as herein set forth.

In testimony whereof I have signed my name to thisspecification in the presenceof two subscribing witnesses.

OTTO FISCHER. Witnesses Dr. EMIL BosTHoRN, EMIL HENZEL. 

